Smart Tubes have been used to bank both blood and bone marrow samples in clinical trials and in clinical studies. The Proteomic Stabilizer PROT1 (each Smart Tube contains an ampoule with 1.4ml of PROT1) is also available in bottle format and PROT1 in bottle format has also been used to bank blood and bone marrow samples in clinical studies. Below are some of the references from our Publications Page and our Online Store:
Janssen Pharma used Smart Tubes to bank bone marrow and blood samples from their clinical trial of Daratumumab in multiple meyloma:
Adams et al, "High‐Parameter Mass Cytometry Evaluation of Relapsed/Refractory Multiple Myeloma Patients Treated with Daratumumab Demonstrates Immune Modulation as a Novel Mechanism of Action"
Janssen Pharma methods paper on the same:
Smets, Tina, et al. "Deep Profiling of the Immune System of Multiple Myeloma Patients Using Cytometry by Time-of-Flight (CyTOF)." Multiple Myeloma. Humana Press, New York, NY, 2018. 47-54.
Clinical studies and methods papers on banking bone marrow samples with our Proteomic Stabilizer PROT1 (each Smart Tube contains an ampoule with 1.4ml of PROT1):
Behbehani et al, Cytometry Part A, 2012
Behbehani et al, Cancer Discovery, 2015
Behbehani also published a detailed protocol for staining samples banked in Smart Tube Proteomic Stabilizer for subsequent analysis by CyTOF:
Behbehani, Gregory K. "Cell Cycle Analysis by Mass Cytometry." Cellular Quiescence. Humana Press, New York, NY, 2018. 105-124.
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